Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models

Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models

Auteur: Joel S. Owen, Jill Fiedler-Kelly
Éditeur: Wiley
Édition: 1
Année de publication: 2014
ISBN: 9780470582299

Choisis ta façon de lire

0

Payer avec Klarna
Garantie satisfait ou remboursé de 14 jours
This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.
• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects
• Provides examples of nonlinear modeling concepts and estimation basics with discussion on  the model building process and applications of empirical Bayesian estimates in the drug development environment
• Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control
• Has datasets, programming code, and practice exercises with solutions, available on a supplementary website

Tu pourrais aussi aimer