Ribosome-inactivating Proteins

Ribosome-inactivating Proteins

Tekijä: Fiorenzo Stirpe, Douglas Lappi
Kustantaja: Wiley
Painos: 1
Julkaisuvuosi: 2014
ISBN: 9781118125656

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Maksa Klarnalla
14 päivän palautusoikeus
This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.

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