Key Features:
- Broad assessment of serpin activity from prokaryotes to complex metazoans
- Comprehensive analysis of the relationships between serpin structures, conformational rearrangements and inhibitory functions
- Insight into the diversity of serpin biology by functional studies in different types of model systems
- Detailed assessment of human diseases resulting from serpin gain-and loss-of-function mutations, including the serpinopathies, rare homozygous null variants and haplo-insufficiency states
- Contributions from major investigators in the fields of serpin biology
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