Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts.
- Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations
- Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts
- Covers design criteria, typical profile of current macrocycles, applications, and limitations
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