PROTEINOID PROTO-NEURAL NETWORKS

Proteinoid Proto-Neural Networks explores the emergence of electrical activity, spiking behavior, and adaptive responses, supported by electrochemical, optical, and acoustic studies that reveal proteinoid-based logic, memory, and learning. It demonstrates how proteinoids, which are synthetic polymers formed from amino acids under high temperature, self-organize into excitable microspheres and assemble into protoneural networks capable of unconventional computation. By blending experimental biophysics with neuromorphic modeling and unconventional computing theory, this monograph establishes proteinoid systems as a platform for wetware computing and the study of emergent intelligence.

This book is perfectly suited for researchers in computer science, computer engineering, soft matter physics, novel materials, neuromorphic engineering and computing, as well as those exploring bio-inspired systems, unconventional computing architectures, and the physicochemical foundations of proto-neural behavior.

Contents:

• Preface
• About the Authors
• Background:
  • What are Proteinoids?
  • Methods and Protocols
• Morphology:
  • Morphologies of Proteinoids
  • Influence of Proteinoids on Calcium Carbonate Polymorphs Precipitation in Supersaturated Solutions
  • Low Frequency Electrical Waves in Ensembles of Proteinoid Microspheres
• Neural Like Activity:
  • Light-Induced Spiking of Proteinoids
  • Proteinoid Microspheres as Protoneural Networks
  • On Interaction of Proteinoids with Simulated Neural Networks
  • Chondroitin Sulfate Modulation of Proteinoid Microsphere Electrical Activity and Neuromorphic Computing Applications
  • Investigation of Proteinoid Microspheres Based on Frequency Response
  • Effects of Omeprazole on Proteinoid Electrical Spiking: Quantification, Mechanisms, and Logic-Like Abstractions
  • Spike Trains in PANI-Proteinoid Nanomaterials With Different Light Pulse Rates
  • Blockage of Action Potential-Like Spiking in D₂O-Suspended Proteinoid Microspheres
  • On Effect of Chloroform on Electrical Activity of Proteinoids
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  • Learning:
    • Learning in Ensembles of Proteinoid Microspheres
    • Memfractance of Proteinoids
  • Computing:
    • Logical Gates in Ensembles of Proteinoid Microspheres
    • Light-Induced Spiking in Proteinoids Yields Boolean Gates
    • Recognition of Sounds by Ensembles of Proteinoids
    • Transfer Functions of Proteinoid Microspheres
    • Optical Recognition of the English Alphabet Using Proteinoids
    • On the Response of Proteinoid Ensembles to Fibonacci Sequences
  • Advancing Proto-Neural Networks with Proto-Dendrites and Proto-Axons:
    • Serotonergic Mechanisms in Proteinoid-Based Protocells
    • Proteinoids–Polyaniline Interaction with Stimulated Neurons on Living and Plastic Surfaces
    • Proteinoid-Polyaniline Neuromorphic Composites for Audio Recognition
    • Morphological and Electrical Properties of Proteinoid–Actin Networks
    • Thermosensory Spiking Activity of Proteinoid Microspheres Cross-Linked by Actin Filaments
  • Bibliography
  • Index

  Readership: For academic researchers, faculty members, graduate students and R&D industrial professionals working on proto-neural behavior, unconventional computing, neuromorphic computing, neuromorphic engineering, neuromorphic hardware, wetware computing, computer science, computer engineering, soft matter physics, novel materials, synthetic biology, bioelectronics, and biotechnology.