SELECTED PAPERS OF FREDERICK SANGER (V1)

SELECTED PAPERS OF FREDERICK SANGER (V1)

Författare: Dowding Margaret, Sanger Frederick
Förlag: World Scientific Publishing Company
Utgivningsår: 1996
ISBN: 9789810224301

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This important volume is mainly concerned with the development of methods for “sequencing” — that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.

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