FUNDAMENTALS OF RADIATION BIOLOGY

Fundamentals of Radiation Biology presents a contemporary, comprehensive review of the interactions between ionizing radiations and biological materials, tracking the consequences to three inevitable endpoints: cell restitution, cell death, or cell transformation.

The introductory narrative is followed by examination of larger scale phenomena including tissue responses to radiation injury, organ failure modes, and resultant human illness including cancer. Ultimately, Fundamentals of Radiation Biology considers circumstantial radiation incidents impacting biological systems including radiological terrorism and radiation pollution remediation. Chapters presenting an overview of carcinogenesis and radiation therapy techniques based in radiobiology discuss two significant expansions central to the concerns of the text.

This book takes an unprecedented narrative approach to radiobiology; each chapter expands on the fundamentals surveyed previously to lead the reader steadily to a panorama of radiation biocomplexity. No biological event happens in isolation. Actions evoke reactions that alter structures and cause living systems to adapt. It also examines the components constituting mammalian radiation response machinery and correlates them with resultant physiological behaviors.

Contents:

• The Origins of Radiation
• Interactions Between Radiation and Absorbing Materials
• Radiation Chemistry
• The Biochemistry of DNA Repair
• Higher Order Biology and Radiation Damage
• Modeling Radiation Biology
• Applications of Dose Response Models
• In vivo Radiation Response
• Radiation and Cancer Biology
• Radiation Therapy
• Radiation Safety

Readership: Medical students, radiologic technology students, cancer oncology researchers, medical physics residents, Physicists.

Key Features:

• Includes the biology, chemistry, mathematics, and physics that form the foundations of radiation biology
• Includes state-of-the-art research results and current hypotheses
• Presents an engaging narrative that enhances the accessibility of difficult subject matter