Structure and Function of Intrinsically Disordered Proteins

Structure and Function of Intrinsically Disordered Proteins

Forfatter: Peter Tompa, Alan Fersht
Forlag: CRC Press
Utgave: 1
Utgivelsesår: 2009
ISBN: 9780367841126

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The existence and functioning of intrinsically disordered proteins (IDPs) challenge the classical structure-function paradigm that equates function with a well-defined 3D structure. Uncovering the disordered complement of proteomes and understanding their functioning can extend the structure-function paradigm to herald new breakthroughs in drug dev

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