Optimization Methods in Metabolic Networks

Optimization Methods in Metabolic Networks

Auteur: Costas D. Maranas, Ali R. Zomorrodi
Uitgever: Wiley
Editie: 1
Publicatiedatum: 2016
ISBN: 9781119028499

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Provides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks 
  • Organizes, for the first time, the fundamentals of mathematical optimization in the context of metabolic network analysis
  • Reviews the fundamentals of different classes of optimization problems including LP, MILP, MLP and MINLP
  • Explains the most efficient ways of formulating a biological problem using mathematical optimization
  • Reviews a variety of relevant problems in metabolic network curation, analysis and redesign with an emphasis on details of optimization formulations
  • Provides a detailed treatment of bilevel optimization techniques for computational strain design and other relevant problems

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