Randomized Phase II Cancer Clinical Trials

Randomized Phase II Cancer Clinical Trials

Auteur: Sin-Ho Jung
Éditeur: CRC Press
Édition: 1
Année de publication: 2013
ISBN: 9781439871850

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In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biosta

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