Randomized Phase II Cancer Clinical Trials

Randomized Phase II Cancer Clinical Trials

Autor: Sin-Ho Jung
Editorial: CRC Press
Edición: 1
Fecha de publicación: 2013
ISBN: 9781439871850

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In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biosta

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