Plant-derived Anticancer Drugs

Enhanced approaches for using plant-derived molecules as a more promising cancer treatment alternative, with lower costs and fewer side effects

Plant-derived Anticancer Drugs discusses the current scenario of cancer, the limitations of synthetic drugs, and the potential of plant-derived molecules in cancer treatment, highlighting a variety of approaches, such as biodegradable nano and quantum dot-based materials, that enhance the therapeutic efficacy of plant-derived molecules to improve solubility, applicability, target-specific delivery, and overall efficacy.

The book begins by discussing the preclinical and clinical utilization of synthetic drugs in cancer therapy, highlighting their mechanisms of action, therapeutic outcomes, limitations, and future perspectives. The book then provides a snapshot of the major drugs approved by the FDA which have historically served as the cornerstone of center treatment, and provides a clinical evidence-based analysis of their survival outcomes. Next, the current role, acceptance, advancements, and challenges of using plant-derived molecules in cancer therapy are reviewed.

Contributed to by international experts in the field, Plant-derived Anticancer Drugs continues to cover sample topics including:

• Advancements in anti-cancer drug development due to genomics, biotechnology, and systems biology
• Integrative approaches which leverage the cytotoxic precision of synthetic drugs alongside the multitargeted and often less toxic nature of phytochemicals
• Optimization of phytochemicals with high anticancer potential to reduce drug discovery timelines and associated costs
• Integration of Artificial Intelligence (AI) and plant-derived bioactive compounds
• Ability of plant-derived molecules and herbal formulations to target multiple pathways involved in cancer progression, such as cell proliferation, apoptosis, angiogenesis, and metastasis

Plant-derived Anticancer Drugs is a completely comprehensive and up-to-date reference on the subject, ideal for natural products chemists, medicinal chemists, biochemists, and cancer researchers in academia and industry. The book is also valuable reading for graduates and undergraduates studying nanotechnology, phytochemistry, pharmacology, oncology, and toxicology.