Randomized Phase II Cancer Clinical Trials

Randomized Phase II Cancer Clinical Trials

Autore: Sin-Ho Jung
Editore: CRC Press
Edizione: 1
Data di pubblicazione: 2013
ISBN: 9781439871850

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In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biosta

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