Repeat Amino Acid Sequences in Proteins

Repeat Amino Acid Sequences in Proteins

Autore: Vladimir N. Uversky, Munishwar Nath Gupta
Editore: CRC Press
Edizione: 1
Data di pubblicazione: 2025
ISBN: 9781032824451

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Repeat amino acid sequences are important in protein structure, disorder, function and evolution. Repeats of some amino acids exist in proteomes across species.

This volume highlights:

  • Which repeat sequences have pathogenic consequences and why?
  • Repeats which lead to surface hydrophobic clusters and their importance
  • Role of aromatic amino acid clusters in protein‐protein and protein‐drug interactions
  • Cell‐penetrating peptides and Elastin‐like peptides
  • Unusual phenomenon of fluorescence observed with repeats of some non‐aromatic amino acids
  • The use of residue cluster classes to represent protein structure and model structure‐function relationships.

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