Applied Surrogate Endpoint Evaluation Methods with SAS and R

Applied Surrogate Endpoint Evaluation Methods with SAS and R

Forfatter: Ziv Shkedy, Marc Buyse, Geert Molenberghs, Tomasz Burzykowski, Ariel Alonso, Theophile Bigirumurame, Leacky Muchene, Nolen Joy Perualila, Wim Van der Elst
Forlag: CRC Press
Udgave: 1
Udgivelsesdato: 2016
ISBN: 9780367736552

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An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment’s efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.

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